LUPORAL CAPSULE is a combination of Tegafur and Uracil which belongs to the group of medicines called Thymidylate synthase inhibitors. It is used with calcium folinate to manage metastatic colorectal cancer which is a type of cancer that begins in the colon or rectum and spreads to other parts of the body and characterized by symptoms such as rectal bleeding, narrow stools, persistent abdominal pain and unexplained weight loss.
Along with this management, your doctor might advise you for a liver function test to assess the function of your liver. LUPORAL CAPSULE is not recommended for use in patients with severe hepatic impairment, bone marrow suppression from previous radiotherapy or dihydropyrimidine dehydrogenase deficiency disease (a severe neurological disease marked by seizures).
Before taking LUPORAL CAPSULE, inform your doctor if you have heart, kidney or liver disease. LUPORAL CAPSULE is not recommended for use in pregnant and breastfeeding women and it is also not recommended for use in children and adolescents (aged below 18 years).
This medicine should be used with caution in elderly patients (aged 75 years or above) with age-related impaired kidney, liver or heart function and other concomitant medications or diseases.
The most common side effects of taking LUPORAL CAPSULE are nausea, diarrhea, constipation, stomach pain, headache, dizziness and dry skin. Consult your doctor if any of the side effects get worse.
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